Alireza Hassani Najafabadi

Ceballos-González CF, Bolívar-Monsalve EJ, Velásquez-Marín S, Rendón-Moreno II, Mora-Rizo A, Quevedo-Moreno DA, Hassani Najafabadi A, Khademhosseini A, Weiss PS, Alvarez MM, Trujillo-de Santiago G. 2025. Chaos-Assisted Production of Micro-Architected Spheres (CAPAS) Small. 2025 Jan;21(1):e2402221. doi: 10.1002/smll.202402221. Epub 2024 Aug 19., ,

Eftekharifar M, Heidari R, Mohaghegh N, Najafabadi AH, Heidari H. 2025. Advances in photoactivated carbon-based nanostructured materials for targeted cancer therapy Adv Drug Deliv Rev. 2025 Jul;222:115604. doi: 10.1016/j.addr.2025.115604. Epub 2025 May 10., ,

Garrett A, Darzi N, Deshmukh A, Rosenfeld N, Goldman O, Adler L, Bab-Dinitz E, Singer O, Hassani Najafabadi A, Wong CW, Bose S, Randon PM, Bustamante F, Larios R, Brandis A, Mehlman T, Smaglo B, Chang P, Oliva J, Haymaker C, Nagawekar L, Wu SR, Huang Y, Shen A, Vora A, Padilla JF, Pfeffer A, Sutherland G, Starr M, Zimmers T, Zhu Y, Morizio J, Erez A, Shen X. 2025. Vagal blockade of the brain-liver axis deters cancer-associated cachexia Cell. 2025 Oct 16;188(21):6044-6063.e24. doi: 10.1016/j.cell.2025.07.016. Epub 2025 Aug 7., ,

Godau B, Jardim A, Pagan E, Hadisi Z, Dabiri SMH, Askari E, Walsh T, Hassani Najafabadi A, Manji K, Rostami M, Azimzadeh M, Armstrong DG, Khademhosseini A, Akbari M. 2025. In vivo validation of a smart sensor-enabled dressing for remote wound monitoring Biosens Bioelectron. 2025 Oct 1;285:117474. doi: 10.1016/j.bios.2025.117474. Epub 2025 Apr 14., ,

Jaberi A, Ghelich P, Samandari M, Kheirabadi S, Ataie Z, Kedzierski A, Hassani Najafabadi A, Tamayol A, Sheikhi A. 2025. Gelatin methacryloyl granular hydrogel scaffolds for skin wound healing Biomater Sci. 2025 Oct 21;13(21):6013-6023. doi: 10.1039/d4bm01062k., ,

Kang N, Hwang J, Jeong D, Choi JH, Thangam R, Min S, Hong H, Kim D, Rha H, Lee S, Jung H, Kim T, Zare I, Jung HJ, Najafabadi AH, Jung HD, Zhang K, Zhao P, Bian L, Kim HK, Kim JS, Song G, Yoon J, Park SG, Jang WY, Kang H. 2025. Ligand Inter-Relation Analysis Via Graph Theory Predicts Macrophage Response Adv Mater. 2025 Mar;37(10):e2414356. doi: 10.1002/adma.202414356. Epub 2024 Dec 24., ,

Kim K, Min S, Thangam R, Tag KR, Lee HJ, Heo J, Jung H, Swe TT, Zare I, Song G, Najafabadi AH, Lee J, Jung HD, Kim JS, Hur S, Song HC, Park SG, Zhang K, Zhao P, Bian L, Kim SH, Yoon J, Ahn JP, Kim HK, Kang H. 2025. Dynamic hierarchical ligand anisotropy for competing macrophage regulation in vivo Bioact Mater. 2025 Jan 19;47:121-135. doi: 10.1016/j.bioactmat.2025.01.009. eCollection 2025 May., ,

Maity S, Bhuyan T, Jewell C, Kawakita S, Sharma S, Nguyen HT, Hassani Najafabadi A, Ermis M, Falcone N, Chen J, Mandal K, Khorsandi D, Yilgor C, Choroomi A, Torres E, Mecwan M, John JV, Akbari M, Wang Z, Moniz-Garcia D, Quiñones-Hinojosa A, Jucaud V, Dokmeci MR, Khademhosseini A. 2025. Recent Developments in Glioblastoma-On-A-Chip for Advanced Drug Screening Applications Small. 2025 Jan;21(1):e2405511. doi: 10.1002/smll.202405511. Epub 2024 Nov 13., ,

Maity S, Hassani Najafabadi A, Kawakita S, Khorsandi D, Yilgor C, Jewell C, Mohaghegh N, Dokmeci MR, Khademhosseini A, Jucaud V. 2025. Lymph node paracortex-inspired on-a-chip recapitulating immunosenescence: a cancer vaccine immunogenicity and antitumoral efficacy screening platform Lab Chip. 2025 Dec 9. doi: 10.1039/d5lc00533g. Online ahead of print., ,

Mohaghegh N, Iyer A, Wang E, Balajam NZ, Kang H, Akbari M, Barnhill MS, Khademhosseini A, Pearson RM, Hassani Najafabadi A. 2025. Apigenin-loaded nanoparticles for obesity intervention through immunomodulation and adipocyte browning J Control Release. 2025 Jun 10;382:113670. doi: 10.1016/j.jconrel.2025.113670. Epub 2025 Apr 3., ,

Montazerian H, Davoodi E, Wang C, Lorestani F, Li J, Haghniaz R, Sampath RR, Mohaghegh N, Khosravi S, Zehtabi F, Zhao Y, Hosseinzadeh N, Liu T, Hsiai TK, Najafabadi AH, Langer R, Anderson DG, Weiss PS, Khademhosseini A, Gao W. 2025. Boosting hydrogel conductivity via water-dispersible conducting polymers for injectable bioelectronics Nat Commun. 2025 Apr 22;16(1):3755. doi: 10.1038/s41467-025-59045-1., ,

Nguyen HT, Tirpakova Z, Peirsman A, Maity S, Falcone N, Kawakita S, Jeon K, Khorsandi D, Rashad A, Farhadi N, Mandal K, Ermis M, Herculano RD, Najafabadi AH, Dokmeci MR, De Barros NR, Khademhosseini A, Jucaud V. 2025. Embolization-on-a-chip: novel vascularized liver tumor model for evaluation of cellular and cytokine response to embolic agents Biofabrication. 2025 Sep 29;17(4). doi: 10.1088/1758-5090/adfbc3., ,

Sanati M, Pieterman I, Levy N, Akbari T, Tavakoli M, Hassani Najafabadi A, Amin Yavari S. 2025. Osteoimmunomodulation by bone implant materials: harnessing physicochemical properties and chemical composition Biomater Sci. 2025 May 27;13(11):2836-2870. doi: 10.1039/d5bm00357a., ,

Ghelich P, Samandari M, Hassani Najafabadi A, Tanguay A, Quint J, Menon N, Ghanbariamin D, Saeedinejad F, Alipanah F, Chidambaram R, Krawetz R, Nuutila K, Toro S, Barnum L, Jay GD, Schmidt TA, Tamayol A. 2024. Dissolvable Immunomodulatory Microneedles for Treatment of Skin Wounds Adv Healthc Mater. 2024 Jun;13(16):e2302836. doi: 10.1002/adhm.202302836. Epub 2024 Mar 17., ,

Kim C, Kang N, Min S, Thangam R, Lee S, Hong H, Kim K, Kim SY, Kim D, Rha H, Tag KR, Lee HJ, Singh N, Jeong D, Hwang J, Kim Y, Park S, Lee H, Kim T, Son SW, Park S, Karamikamkar S, Zhu Y, Hassani Najafabadi A, Chu Z, Sun W, Zhao P, Zhang K, Bian L, Song HC, Park SG, Kim JS, Lee SY, Ahn JP, Kim HK, Zhang YS, Kang H. 2024. Modularity-based mathematical modeling of ligand inter-nanocluster connectivity for unraveling reversible stem cell regulation Nat Commun. 2024 Dec 23;15(1):10665. doi: 10.1038/s41467-024-54557-8., ,

Mahmoodi M, Ali Darabi M, Mohaghegh N, Erdem A, Ahari A, Abbasgholizadeh R, Tavafoghi M, Hashemian PM, Hosseini V, Iqbal J, Haghniaz R, Montazerian H, Jahangiry J, Nasrolahi F, Mirjafari A, Pagan E, Akbari M, Bae H, John JV, Heidari H, Khademhosseini A, Hassani Najafabadi A. 2024. Egg White Photocrosslinkable Hydrogels as Versatile Bioinks for Advanced Tissue Engineering Applications Adv Funct Mater. 2024 Aug 8;34(32):2315040. doi: 10.1002/adfm.202315040. Epub 2024 May 13., ,

Mohaghegh N, Ahari A, Buttles C, Davani S, Hoang H, Huang Q, Huang Y, Hosseinpour B, Abbasgholizadeh R, Cottingham AL, Farhadi N, Akbari M, Kang H, Khademhosseini A, Jucaud V, Pearson RM, Hassani Najafabadi A. 2024. Simvastatin-Loaded Polymeric Nanoparticles: Targeting Inflammatory Macrophages for Local Adipose Tissue Browning in Obesity Treatment ACS Nano. 2024 Oct 8;18(40):27764-27781. doi: 10.1021/acsnano.4c10742. Epub 2024 Sep 29., ,

Razzaghi M, Ninan JA, Azimzadeh M, Askari E, Najafabadi AH, Khademhosseini A, Akbari M. 2024. Remote-Controlled Sensing and Drug Delivery via 3D-Printed Hollow Microneedles Adv Healthc Mater. 2024 Sep;13(23):e2400881. doi: 10.1002/adhm.202400881. Epub 2024 Jun 4., ,

de Barros NR, Darabi MA, Ma X, Diltemiz SE, Ermis M, Hassani Najafabadi A, Nadine S, Banton EA, Mandal K, Abbasgholizadeh R, Falcone N, Mano JF, Nasiri R, Herculano RD, Zhu Y, Ostrovidov S, Lee J, Kim HJ, Hosseini V, Dokmeci MR, Ahadian S, Khademhosseini A. 2023. Enhanced Maturation of 3D Bioprinted Skeletal Muscle Tissue Constructs Encapsulating Soluble Factor-Releasing Microparticles Macromol Biosci. 2023 Dec;23(12):e2300276. doi: 10.1002/mabi.202300276. Epub 2023 Aug 17., ,

Godau B, Samimi S, Seyfoori A, Samiei E, Khani T, Naserzadeh P, Najafabadi AH, Lesha E, Majidzadeh-A K, Ashtari B, Charest G, Morin C, Fortin D, Akbari M. 2023. A Drug-Eluting Injectable NanoGel for Localized Delivery of Anticancer Drugs to Solid Tumors Pharmaceutics. 2023 Aug 31;15(9):2255. doi: 10.3390/pharmaceutics15092255., ,

Lee S, Yoo J, Bae G, Thangam R, Heo J, Park JY, Choi H, Kim C, An J, Kim J, Mun KR, Shin S, Zhang K, Zhao P, Kim Y, Kang N, Han SB, Kim D, Yoon J, Kang M, Kim J, Yang L, Karamikamkar S, Kim J, Zhu Y, Najafabadi AH, Song G, Kim DH, Lee KB, Oh SJ, Jung HD, Song HC, Jang WY, Bian L, Chu Z, Yoon J, Kim JS, Zhang YS, Kim Y, Jang HS, Kim S, Kang H. 2023. Photonic control of ligand nanospacing in self-assembly regulates stem cell fate Bioact Mater. 2023 Dec 26;34:164-180. doi: 10.1016/j.bioactmat.2023.12.011. eCollection 2024 Apr., ,

Mecwan M, Haghniaz R, Najafabadi AH, Mandal K, Jucaud V, John JV, Khademhosseini A. 2023. Thermoresponsive shear-thinning hydrogel (T-STH) hemostats for minimally invasive treatment of external hemorrhages Biomater Sci. 2023 Jan 31;11(3):949-963. doi: 10.1039/d2bm01559e., ,

Mohaghegh N, Ahari A, Zehtabi F, Buttles C, Davani S, Hoang H, Tseng K, Zamanian B, Khosravi S, Daniali A, Kouchehbaghi NH, Thomas I, Serati Nouri H, Khorsandi D, Abbasgholizadeh R, Akbari M, Patil R, Kang H, Jucaud V, Khademhosseini A, Hassani Najafabadi A. 2023. Injectable hydrogels for personalized cancer immunotherapies Acta Biomater. 2023 Dec;172:67-91. doi: 10.1016/j.actbio.2023.10.002. Epub 2023 Oct 6., ,

Montazerian H, Hassani Najafabadi A, Davoodi E, Seyedmahmoud R, Haghniaz R, Baidya A, Gao W, Annabi N, Khademhosseini A, Weiss PS. 2023. Poly-Catecholic Functionalization of Biomolecules for Rapid Gelation, Robust Injectable Bioadhesion, and Near-Infrared Responsiveness Adv Healthc Mater. 2023 Jul;12(17):e2203404. doi: 10.1002/adhm.202203404. Epub 2023 Mar 17., ,

Nazarzadeh Zare E, Khorsandi D, Zarepour A, Yilmaz H, Agarwal T, Hooshmand S, Mohammadinejad R, Ozdemir F, Sahin O, Adiguzel S, Khan H, Zarrabi A, Sharifi E, Kumar A, Mostafavi E, Kouchehbaghi NH, Mattoli V, Zhang F, Jucaud V, Najafabadi AH, Khademhosseini A. 2023. Biomedical applications of engineered heparin-based materials Bioact Mater. 2023 Aug 10;31:87-118. doi: 10.1016/j.bioactmat.2023.08.002. eCollection 2024 Jan., ,

Nguyen HT, Peirsman A, Tirpakova Z, Mandal K, Vanlauwe F, Maity S, Kawakita S, Khorsandi D, Herculano R, Umemura C, Yilgor C, Bell R, Hanson A, Li S, Nanda HS, Zhu Y, Najafabadi AH, Jucaud V, Barros N, Dokmeci MR, Khademhosseini A. 2023. Engineered Vasculature for Cancer Research and Regenerative Medicine Micromachines (Basel). 2023 Apr 29;14(5):978. doi: 10.3390/mi14050978., ,

Razzaghi M, Seyfoori A, Pagan E, Askari E, Hassani Najafabadi A, Akbari M. 2023. 3D Printed Hydrogel Microneedle Arrays for Interstitial Fluid Biomarker Extraction and Colorimetric Detection Polymers (Basel). 2023 Mar 10;15(6):1389. doi: 10.3390/polym15061389., ,

Zehtabi F, Montazerian H, Haghniaz R, Tseng K, Mohaghegh N, Mandal K, Zamanian B, Dokmeci MR, Akbari M, Hassani Najafabadi A, Kim HJ, Khademhosseini A. 2023. Sodium Phytate-Incorporated Gelatin-Silicate Nanoplatelet Composites for Enhanced Cohesion and Hemostatic Function of Shear-Thinning Biomaterials Macromol Biosci. 2023 Jan;23(1):e2200333. doi: 10.1002/mabi.202200333. Epub 2022 Oct 26., ,

Aikins ME, Qin Y, Dobson HE, Najafabadi AH, Lyu K, Xu Y, Xin Y, Schwendeman A, Wicha MS, Chang AE, Li Q, Moon JJ. 2022. Cancer stem cell antigen nanodisc cocktail elicits anti-tumor immune responses in melanoma J Control Release. 2022 Nov;351:872-882. doi: 10.1016/j.jconrel.2022.09.061. Epub 2022 Oct 10., ,

Ghelich P, Kazemzadeh-Narbat M, Najafabadi AH, Samandari M, Memic A, Tamayol A. 2022. (Bio)manufactured Solutions for Treatment of Bone Defects with Emphasis on US-FDA Regulatory Science Perspective Adv Nanobiomed Res. 2022 Apr;2(4):2100073. doi: 10.1002/anbr.202100073. Epub 2022 Jan 5., ,

Liao F, Zhang J, Hu Y, Najafabadi AH, Moon JJ, Wicha MS, Kaspo B, Whitfield J, Chang AE, Li Q. 2022. Efficacy of an ALDH peptide-based dendritic cell vaccine targeting cancer stem cells Cancer Immunol Immunother. 2022 Aug;71(8):1959-1973. doi: 10.1007/s00262-021-03129-6. Epub 2022 Jan 31., ,

Zare I, Yaraki MT, Speranza G, Najafabadi AH, Shourangiz-Haghighi A, Nik AB, Manshian BB, Saraiva C, Soenen SJ, Kogan MJ, Lee JW, Apollo NV, Bernardino L, Araya E, Mayer D, Mao G, Hamblin MR. 2022. Gold nanostructures: synthesis, properties, and neurological applications Chem Soc Rev. 2022 Apr 4;51(7):2601-2680. doi: 10.1039/d1cs01111a., ,

Najafabadi AH, Abadi ZIN, Aikins ME, Foulds KE, Donaldson MM, Yuan W, Okeke EB, Nam J, Xu Y, Weerappuli P, Hetrick T, Adams D, Lester PA, Salazar AM, Barouch DH, Schwendeman A, Seder RA, Moon JJ. 2021. Vaccine nanodiscs plus polyICLC elicit robust CD8+ T cell responses in mice and non-human primates J Control Release. 2021 Sep 10;337:168-178. doi: 10.1016/j.jconrel.2021.07.026. Epub 2021 Jul 16., ,

Chen Z, Wholey WY, Hassani Najafabadi A, Moon JJ, Grigorova I, Chackerian B, Cheng W. 2020. Self-Antigens Displayed on Liposomal Nanoparticles above a Threshold of Epitope Density Elicit Class-Switched Autoreactive Antibodies Independent of T Cell Help J Immunol. 2020 Jan 15;204(2):335-347. doi: 10.4049/jimmunol.1801677. Epub 2019 Dec 13., ,

Hassani Najafabadi A, Zhang J, Aikins ME, Najaf Abadi ZI, Liao F, Qin Y, Okeke EB, Scheetz LM, Nam J, Xu Y, Adams D, Lester P, Hetrick T, Schwendeman A, Wicha MS, Chang AE, Li Q, Moon JJ. 2020. Cancer Immunotherapy via Targeting Cancer Stem Cells Using Vaccine Nanodiscs Nano Lett. 2020 Oct 14;20(10):7783-7792. doi: 10.1021/acs.nanolett.0c03414. Epub 2020 Sep 14., ,

Kuai R, Singh PB, Sun X, Xu C, Najafabadi AH, Scheetz L, Yuan W, Xu Y, Hong H, Keskin DB, Wu CJ, Jain R, Schwendeman A, Moon JJ. 2020. Robust anti-tumor T cell response with efficient intratumoral infiltration by nanodisc cancer immunotherapy Adv Ther (Weinh). 2020 Sep;3(9):2000094. doi: 10.1002/adtp.202000094. Epub 2020 Jun 23., ,

Okeke EB, Louttit C, Fry C, Najafabadi AH, Han K, Nemzek J, Moon JJ. 2020. Inhibition of neutrophil elastase prevents neutrophil extracellular trap formation and rescues mice from endotoxic shock Biomaterials. 2020 Apr;238:119836. doi: 10.1016/j.biomaterials.2020.119836. Epub 2020 Feb 3., ,

Scheetz L, Kadiyala P, Sun X, Son S, Hassani Najafabadi A, Aikins M, Lowenstein PR, Schwendeman A, Castro MG, Moon JJ. 2020. Synthetic High-density Lipoprotein Nanodiscs for Personalized Immunotherapy Against Gliomas Clin Cancer Res. 2020 Aug 15;26(16):4369-4380. doi: 10.1158/1078-0432.CCR-20-0341. Epub 2020 May 21., ,

Kuai R, Sun X, Yuan W, Ochyl LJ, Xu Y, Hassani Najafabadi A, Scheetz L, Yu MZ, Balwani I, Schwendeman A, Moon JJ. 2018. Dual TLR agonist nanodiscs as a strong adjuvant system for vaccines and immunotherapy J Control Release. 2018 Jul 28;282:131-139. doi: 10.1016/j.jconrel.2018.04.041. Epub 2018 Apr 25., ,

Tamayol A, Hassani Najafabadi A, Mostafalu P, Yetisen AK, Commotto M, Aldhahri M, Abdel-Wahab MS, Najafabadi ZI, Latifi S, Akbari M, Annabi N, Yun SH, Memic A, Dokmeci MR, Khademhosseini A. 2017. Biodegradable elastic nanofibrous platforms with integrated flexible heaters for on-demand drug delivery Sci Rep. 2017 Aug 23;7(1):9220. doi: 10.1038/s41598-017-04749-8., ,

Hassani Najafabadi A, Azodi-Deilami S, Abdouss M, Payravand H, Farzaneh S. 2015. Synthesis and evaluation of hydroponically alginate nanoparticles as novel carrier for intravenous delivery of propofol J Mater Sci Mater Med. 2015 Mar;26(3):145. doi: 10.1007/s10856-015-5452-0. Epub 2015 Mar 6., ,

Tamayol A, Najafabadi AH, Aliakbarian B, Arab-Tehrany E, Akbari M, Annabi N, Juncker D, Khademhosseini A. 2015. Bioactive Fibers: Hydrogel Templates for Rapid Manufacturing of Bioactive Fibers and 3D Constructs (Adv. Healthcare Mater. 14/2015) Adv Healthc Mater. 2015 Oct;4(14):2050. doi: 10.1002/adhm.201570082., ,

Tamayol A, Najafabadi AH, Aliakbarian B, Arab-Tehrany E, Akbari M, Annabi N, Juncker D, Khademhosseini A. 2015. Hydrogel Templates for Rapid Manufacturing of Bioactive Fibers and 3D Constructs Adv Healthc Mater. 2015 Oct;4(14):2146-2153. doi: 10.1002/adhm.201500492. Epub 2015 Aug 25., ,

Akbari M, Tamayol A, Laforte V, Annabi N, Hassani Najafabadi A, Khademhosseini A, Juncker D. 2014. Composite Living Fibers for Creating Tissue Constructs Using Textile Techniques Adv Funct Mater. 2014 Jul 9;24(26):4060-4067. doi: 10.1002/adfm.201303655., ,

Hassani Najafabadi A, Abdouss M, Faghihi S. 2014. Synthesis and evaluation of PEG-O-chitosan nanoparticles for delivery of poor water soluble drugs: ibuprofen Mater Sci Eng C Mater Biol Appl. 2014 Aug 1;41:91-9. doi: 10.1016/j.msec.2014.04.035. Epub 2014 Apr 26., ,

Najafabadi AH, Tamayol A, Annabi N, Ochoa M, Mostafalu P, Akbari M, Nikkhah M, Rahimi R, Dokmeci MR, Sonkusale S, Ziaie B, Khademhosseini A. 2014. Biodegradable nanofibrous polymeric substrates for generating elastic and flexible electronics Adv Mater. 2014 Sep 3;26(33):5823-30. doi: 10.1002/adma.201401537. Epub 2014 Jul 19., ,