Education/CredentialsPhD: University of Wisconsin-Madison (Biochemistry)BS: University of Puerto Rico-Mayagüez (Industrial Biotechnology) Contact Information Email rodri3ju@ucmail.uc.edu Peer Reviewed Publications Carminati, Manuel; Rodríguez-Molina, Juan B; Manav, M Cemre; Bellini, Dom; Passmore, Lori A 2023. A direct interaction between CPF and RNA Pol II links RNA 3' end processing to transcription. Molecular cell, 83 24, 4461-4478.e13Rodríguez-Molina, Juan B; Turtola, Matti 2023. Birth of a poly(A) tail: mechanisms and control of mRNA polyadenylation. FEBS open bio, 13 7, 1140-1153Rodríguez-Molina, Juan B; West, Steven; Passmore, Lori A 2023. Knowing when to stop: Transcription termination on protein-coding genes by eukaryotic RNAPII. Molecular cell, 83 3, 404-415Rodríguez-Molina, Juan B; O'Reilly, Francis J; Fagarasan, Holly; Sheekey, Eleanor; Maslen, Sarah; Skehel, J Mark; Rappsilber, Juri; Passmore, Lori A 2022. Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF. Molecular cell, 82 13, 2490-2504.e12Kumar, Ananthanarayanan; Yu, Conny W H; Rodríguez-Molina, Juan B; Li, Xiao-Han; Freund, Stefan M V; Passmore, Lori A 2021. Dynamics in Fip1 regulate eukaryotic mRNA 3' end processing. Genes & development, 35 21-22, 1510-1526Lidschreiber, Michael; Easter, Ashley D; Battaglia, Sofia; Rodríguez-Molina, Juan B; Casañal, Ana; Carminati, Manuel; Baejen, Carlo; Grzechnik, Pawel; Maier, Kerstin C; Cramer, Patrick; Passmore, Lori A 2018. The APT complex is involved in non-coding RNA transcription and is distinct from CPF. Nucleic acids research, 46 21, 11528-11538Rodríguez-Molina, Juan B; Tseng, Sandra C; Simonett, Shane P; Taunton, Jack; Ansari, Aseem Z 2016. Engineered Covalent Inactivation of TFIIH-Kinase Reveals an Elongation Checkpoint and Results in Widespread mRNA Stabilization. Molecular cell, 63 3, 433-44Zhang, David W; Mosley, Amber L; Ramisetty, Sreenivasa R; Rodríguez-Molina, Juan B; Washburn, Michael P; Ansari, Aseem Z 2012. Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination. The Journal of biological chemistry, 287 11, 8541-51
Peer Reviewed Publications Carminati, Manuel; Rodríguez-Molina, Juan B; Manav, M Cemre; Bellini, Dom; Passmore, Lori A 2023. A direct interaction between CPF and RNA Pol II links RNA 3' end processing to transcription. Molecular cell, 83 24, 4461-4478.e13Rodríguez-Molina, Juan B; Turtola, Matti 2023. Birth of a poly(A) tail: mechanisms and control of mRNA polyadenylation. FEBS open bio, 13 7, 1140-1153Rodríguez-Molina, Juan B; West, Steven; Passmore, Lori A 2023. Knowing when to stop: Transcription termination on protein-coding genes by eukaryotic RNAPII. Molecular cell, 83 3, 404-415Rodríguez-Molina, Juan B; O'Reilly, Francis J; Fagarasan, Holly; Sheekey, Eleanor; Maslen, Sarah; Skehel, J Mark; Rappsilber, Juri; Passmore, Lori A 2022. Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF. Molecular cell, 82 13, 2490-2504.e12Kumar, Ananthanarayanan; Yu, Conny W H; Rodríguez-Molina, Juan B; Li, Xiao-Han; Freund, Stefan M V; Passmore, Lori A 2021. Dynamics in Fip1 regulate eukaryotic mRNA 3' end processing. Genes & development, 35 21-22, 1510-1526Lidschreiber, Michael; Easter, Ashley D; Battaglia, Sofia; Rodríguez-Molina, Juan B; Casañal, Ana; Carminati, Manuel; Baejen, Carlo; Grzechnik, Pawel; Maier, Kerstin C; Cramer, Patrick; Passmore, Lori A 2018. The APT complex is involved in non-coding RNA transcription and is distinct from CPF. Nucleic acids research, 46 21, 11528-11538Rodríguez-Molina, Juan B; Tseng, Sandra C; Simonett, Shane P; Taunton, Jack; Ansari, Aseem Z 2016. Engineered Covalent Inactivation of TFIIH-Kinase Reveals an Elongation Checkpoint and Results in Widespread mRNA Stabilization. Molecular cell, 63 3, 433-44Zhang, David W; Mosley, Amber L; Ramisetty, Sreenivasa R; Rodríguez-Molina, Juan B; Washburn, Michael P; Ansari, Aseem Z 2012. Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination. The Journal of biological chemistry, 287 11, 8541-51
Carminati, Manuel; Rodríguez-Molina, Juan B; Manav, M Cemre; Bellini, Dom; Passmore, Lori A 2023. A direct interaction between CPF and RNA Pol II links RNA 3' end processing to transcription. Molecular cell, 83 24, 4461-4478.e13Rodríguez-Molina, Juan B; Turtola, Matti 2023. Birth of a poly(A) tail: mechanisms and control of mRNA polyadenylation. FEBS open bio, 13 7, 1140-1153Rodríguez-Molina, Juan B; West, Steven; Passmore, Lori A 2023. Knowing when to stop: Transcription termination on protein-coding genes by eukaryotic RNAPII. Molecular cell, 83 3, 404-415Rodríguez-Molina, Juan B; O'Reilly, Francis J; Fagarasan, Holly; Sheekey, Eleanor; Maslen, Sarah; Skehel, J Mark; Rappsilber, Juri; Passmore, Lori A 2022. Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF. Molecular cell, 82 13, 2490-2504.e12Kumar, Ananthanarayanan; Yu, Conny W H; Rodríguez-Molina, Juan B; Li, Xiao-Han; Freund, Stefan M V; Passmore, Lori A 2021. Dynamics in Fip1 regulate eukaryotic mRNA 3' end processing. Genes & development, 35 21-22, 1510-1526Lidschreiber, Michael; Easter, Ashley D; Battaglia, Sofia; Rodríguez-Molina, Juan B; Casañal, Ana; Carminati, Manuel; Baejen, Carlo; Grzechnik, Pawel; Maier, Kerstin C; Cramer, Patrick; Passmore, Lori A 2018. The APT complex is involved in non-coding RNA transcription and is distinct from CPF. Nucleic acids research, 46 21, 11528-11538Rodríguez-Molina, Juan B; Tseng, Sandra C; Simonett, Shane P; Taunton, Jack; Ansari, Aseem Z 2016. Engineered Covalent Inactivation of TFIIH-Kinase Reveals an Elongation Checkpoint and Results in Widespread mRNA Stabilization. Molecular cell, 63 3, 433-44Zhang, David W; Mosley, Amber L; Ramisetty, Sreenivasa R; Rodríguez-Molina, Juan B; Washburn, Michael P; Ansari, Aseem Z 2012. Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination. The Journal of biological chemistry, 287 11, 8541-51