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Rulang Jiang, PhD

Professor-Affiliate

Pediatrics | College of Medicine

Education/Credentials
  • Bachelor's Degree: Nanjing Normal University
  • Master's Degree: Chinese Academy of Sciences (Genetics)
  • Doctoral Degree: Wesleyan University
Contact Information
Research Interests

Molecular developmental biology.

Peer Reviewed Publications

Lan, Yu; Wu, Zhaoming; Liu, Han; Jiang, Rulang 2024. Lineage-specific requirements of Alx4 function in craniofacial and hair development. Developmental dynamics : an official publication of the American Association of Anatomists, 253 10, 940-948

Lee, Su Jeong; Kim, Ju Ang; Ihn, Hye Jung; Choi, Je-Yong; Kwon, Tae-Yub; Shin, Hong-In; Cho, Eui-Sic; Bae, Yong Chul; Jiang, Rulang; Kim, Jung-Eun; Park, Eui Kyun 2024. The transcription factor BBX regulates phosphate homeostasis through the modulation of FGF23. Experimental & molecular medicine, 56 11, 2436-2448

Perl, Alison J; Liu, Han; Hass, Matthew; Adhikari, Nirpesh; Chaturvedi, Praneet; Hu, Yueh-Chiang; Jiang, Rulang; Liu, Yaping; Kopan, Raphael 2024. Reduced Nephron Endowment in Six2-TGCtg Mice Is Due to Six3 Misexpression by Aberrant Enhancer-Promoter Interactions in the Transgene. Journal of the American Society of Nephrology : JASN, 35 5, 566-577

Iyyanar, Paul P R; Qin, Chuanqi; Adhikari, Nirpesh; Liu, Han; Hu, Yueh-Chiang; Jiang, Rulang; Lan, Yu 2023. Developmental origin of the mammalian premaxilla. Developmental biology, 503 , 1-9

Liu, Lin; Zhou, Yi; Liu, Zhimin; Li, Jiangyuan; Hu, Linghao; He, Leya; Gao, Guannan; Kidd, Brian; Walsh, Alexandra; Jiang, Rulang; Wu, Chaodong; Zhang, Ke; Xie, Linglin 2023. Osr1 Regulates Macrophage-mediated Liver Inflammation in Nonalcoholic Fatty Liver Disease Progression. Cellular and molecular gastroenterology and hepatology, 15 5, 1117-1133

Lofrano-Porto, Adriana; Pereira, Sidney Alcântara; Dauber, Andrew; Bloom, Jordana Cb; Fontes, Audrey N; Asimow, Naomi; de Moraes, Olívia Laquis; Araujo, Petra Ariadne T; Abreu, Ana Paula; Guo, Michael H; De Oliveira, Silviene F; Liu, Han; Lee, Charles; Kuohung, Wendy; Coelho, Michella S; Carroll, Rona S; Jiang, Rulang; Kaiser, Ursula B 2023. OSR1 disruption contributes to uterine factor infertility via impaired Müllerian duct development and endometrial receptivity. The Journal of clinical investigation, 133 23,

Perl, Alison J; Liu, Han; Hass, Matthew; Adhikari, Nirpesh; Chaturvedi, Praneet; Hu, Yueh-Chiang; Jiang, Rulang; Liu, Yaping; Kopan, Raphael 2023. Reduced nephron endowment in the common Six2-TGC tg mouse line is due to Six3 misexpression by aberrant enhancer-promoter interactions in the transgene. bioRxiv : the preprint server for biology, ,

Wurmser, Maud; Madani, Rouba; Chaverot, Nathalie; Backer, Stéphanie; Borok, Matthew; Dos Santos, Matthieu; Comai, Glenda; Tajbakhsh, Shahragim; Relaix, Frédéric; Santolini, Marc; Sambasivan, Ramkumar; Jiang, Rulang; Maire, Pascal 2023. Overlapping functions of SIX homeoproteins during embryonic myogenesis. PLoS genetics, 19 6, e1010781

Xu, Jingyue; Iyyanar, Paul P R; Lan, Yu; Jiang, Rulang 2023. Sonic hedgehog signaling in craniofacial development. Differentiation; research in biological diversity, 133 , 60-76

Iyyanar, Paul P R; Wu, Zhaoming; Lan, Yu; Hu, Yueh-Chiang; Jiang, Rulang 2022. Alx1 Deficient Mice Recapitulate Craniofacial Phenotype and Reveal Developmental Basis of ALX1-Related Frontonasal Dysplasia. Frontiers in cell and developmental biology, 10 , 777887

Lan, Yu; Jiang, Rulang 2022. Mouse models in palate development and orofacial cleft research: Understanding the crucial role and regulation of epithelial integrity in facial and palate morphogenesis. Current topics in developmental biology, 148 , 13-50

Xu, Jingyue; Liu, Han; Lan, Yu; Jiang, Rulang 2022. The transcription factors Foxf1 and Foxf2 integrate the SHH, HGF and TGFβ signaling pathways to drive tongue organogenesis. Development (Cambridge, England), 149 21,

Ihn, Hye Jung; Kim, Ju Ang; Lim, Jiwon; Nam, Sang-Hyeon; Hwang, So Hyeon; Kim, Young Kyung; Kim, Jae-Young; Kim, Jung-Eun; Cho, Eui-Sic; Jiang, Rulang; Park, Eui Kyun 2021. Bobby sox homolog regulates tooth root formation through modulation of dentin sialophosphoprotein. Journal of cellular physiology, 236 1, 480-488

Liu, Han; Xu, Jingyue; Lan, Yu; Lim, Hee-Woong; Jiang, Rulang 2021. The Scleraxis Transcription Factor Directly Regulates Multiple Distinct Molecular and Cellular Processes During Early Tendon Cell Differentiation. Frontiers in cell and developmental biology, 9 , 654397

Xu, Jingyue; Liu, Han; Lan, Yu; Jiang, Rulang 2021. Cis-Repression of Foxq1 Expression Affects Foxf2-Mediated Gene Expression in Palate Development. Frontiers in cell and developmental biology, 9 , 665109

Yue, Minghui; Lan, Yu; Liu, Han; Wu, Zhaoming; Imamura, Toru; Jiang, Rulang 2021. Tissue-specific analysis of Fgf18 gene function in palate development. Developmental dynamics : an official publication of the American Association of Anatomists, 250 4, 562-573

Li, Chaochang; Liu, Han; Hu, Yueh-Chiang; Lan, Yu; Jiang, Rulang 2020. Generation and characterization of Six2 conditional mice. Genesis (New York, N.Y. : 2000), 58 7, e23365

Jia, Shihai; Kwon, Hyuk-Jae Edward; Lan, Yu; Zhou, Jing; Liu, Han; Jiang, Rulang 2016. Bmp4-Msx1 signaling and Osr2 control tooth organogenesis through antagonistic regulation of secreted Wnt antagonists. Developmental biology, 420 1, 110-119

Lan, Yu; Zhang, Nian; Liu, Han; Xu, Jingyue; Jiang, Rulang 2016. Golgb1 regulates protein glycosylation and is crucial for mammalian palate development. Development (Cambridge, England), 143 13, 2344-55

Xu, Jingyue; Liu, Han; Chai, Ok Hee; Lan, Yu; Jiang, Rulang 2016. Osr1 Interacts Synergistically with Wt1 to Regulate Kidney Organogenesis. PloS one, 11 7, e0159597

Xu, Jingyue; Liu, Han; Lan, Yu; Aronow, Bruce J; Kalinichenko, Vladimir V; Jiang, Rulang 2016. A Shh-Foxf-Fgf18-Shh Molecular Circuit Regulating Palate Development. PLoS genetics, 12 1, e1005769

Breidenbach, Andrew P; Aschbacher-Smith, Lindsey; Lu, Yinhui; Dyment, Nathaniel A; Liu, Chia-Feng; Liu, Han; Wylie, Chris; Rao, Marepalli; Shearn, Jason T; Rowe, David W; Kadler, Karl E; Jiang, Rulang; Butler, David L 2015. Ablating hedgehog signaling in tenocytes during development impairs biomechanics and matrix organization of the adult murine patellar tendon enthesis. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 33 8, 1142-51

Dyment, Nathaniel A; Breidenbach, Andrew P; Schwartz, Andrea G; Russell, Ryan P; Aschbacher-Smith, Lindsey; Liu, Han; Hagiwara, Yusuke; Jiang, Rulang; Thomopoulos, Stavros; Butler, David L; Rowe, David W 2015. Gdf5 progenitors give rise to fibrocartilage cells that mineralize via hedgehog signaling to form the zonal enthesis. Developmental biology, 405 1, 96-107

Lan, Yu; Xu, Jingyue; Jiang, Rulang 2015. Cellular and Molecular Mechanisms of Palatogenesis. Current topics in developmental biology, 115 , 59-84

Liu, Han; Xu, Jingyue; Liu, Chia-Feng; Lan, Yu; Wylie, Christopher; Jiang, Rulang 2015. Whole transcriptome expression profiling of mouse limb tendon development by using RNA-seq. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 33 6, 840-8

Xu, Jingyue; Liu, Han; Park, Joo-Seop; Lan, Yu; Jiang, Rulang 2014. Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis. Development (Cambridge, England), 141 7, 1442-52

Zhou, Hao; Zou, Shujuan; Lan, Yu; Fei, Wei; Jiang, Rulang; Hu, Jing 2014. Smad7 modulates TGF? signaling during cranial suture development to maintain suture patency. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 29 3, 716-24

Jia, Shihai; Zhou, Jing; Gao, Yang; Baek, Jin-A; Martin, James F; Lan, Yu; Jiang, Rulang 2013. Roles of Bmp4 during tooth morphogenesis and sequential tooth formation. Development (Cambridge, England), 140 2, 423-32

Liu, Han; Lan, Yu; Xu, Jingyue; Chang, Ching-Fang; Brugmann, Samantha A; Jiang, Rulang 2013. Odd-skipped related-1 controls neural crest chondrogenesis during tongue development. Proceedings of the National Academy of Sciences of the United States of America, 110 46, 18555-60

Zhou, Jing; Gao, Yang; Lan, Yu; Jia, Shihai; Jiang, Rulang 2013. Pax9 regulates a molecular network involving Bmp4, Fgf10, Shh signaling and the Osr2 transcription factor to control palate morphogenesis. Development (Cambridge, England), 140 23, 4709-18

Zhu, Songsong; Chen, Kan; Lan, Yu; Zhang, Nan; Jiang, Rulang; Hu, Jing 2013. Alendronate protects against articular cartilage erosion by inhibiting subchondral bone loss in ovariectomized rats. Bone, 53 2, 340-9

Anderson, Douglas M; George, Rajani; Noyes, Marcus B; Rowton, Megan; Liu, Wenjin; Jiang, Rulang; Wolfe, Scot A; Wilson-Rawls, Jeanne; Rawls, Alan 2012. Characterization of the DNA-binding properties of the Mohawk homeobox transcription factor. The Journal of biological chemistry, 287 42, 35351-9

Bush, Jeffrey O; Jiang, Rulang 2012. Palatogenesis: morphogenetic and molecular mechanisms of secondary palate development. Development (Cambridge, England), 139 2, 231-43

Guillot, Nicolas; Kollins, Dmitrij; Gilbert, Victoria; Xavier, Sandhya; Chen, Jun; Gentle, Madeleine; Reddy, Anand; Bottinger, Erwin; Jiang, Rulang; Rastaldi, Maria Pia; Corbelli, Alessandro; Schlondorff, Detlef 2012. BAMBI regulates angiogenesis and endothelial homeostasis through modulation of alternative TGF? signaling. PloS one, 7 6, e39406

Yu, Cheng-Tai; Tang, Ke; Suh, Jae Mi; Jiang, Rulang; Tsai, Sophia Y; Tsai, Ming-Jer 2012. COUP-TFII is essential for metanephric mesenchyme formation and kidney precursor cell survival. Development (Cambridge, England), 139 13, 2330-9

Baek, Jin-A; Lan, Yu; Liu, Han; Maltby, Kathleen M; Mishina, Yuji; Jiang, Rulang 2011. Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation. Developmental biology, 350 2, 520-31

Gao, Yang; Lan, Yu; Liu, Han; Jiang, Rulang 2011. The zinc finger transcription factors Osr1 and Osr2 control synovial joint formation. Developmental biology, 352 1, 83-91

Kim, Tak-Heun; Lee, Ju-Yeon; Baek, Jin-A; Lee, Jeong-Chae; Yang, Xiao; Taketo, Makoto M; Jiang, Rulang; Cho, Eui-Sic 2011. Constitutive stabilization of ß-catenin in the dental mesenchyme leads to excessive dentin and cementum formation. Biochemical and biophysical research communications, 412 4, 549-55

Lan, Yu; Liu, Han; Ovitt, Catherine E; Jiang, Rulang 2011. Generation of Osr1 conditional mutant mice. Genesis (New York, N.Y. : 2000), 49 5, 419-22

Li, Jingyuan; Huang, Xiaofeng; Xu, Xun; Mayo, Julie; Bringas, Pablo; Jiang, Rulang; Wang, Songling; Chai, Yang 2011. SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis. Development (Cambridge, England), 138 10, 1977-89

Xie, Rong; Jiang, Rulang; Chen, Di 2011. Generation of Axin1 conditional mutant mice. Genesis (New York, N.Y. : 2000), 49 2, 98-102

Zhou, Jing; Gao, Yang; Zhang, Zunyi; Zhang, Yuan; Maltby, Kathleen M; Liu, Zhaoyang; Lan, Yu; Jiang, Rulang 2011. Osr2 acts downstream of Pax9 and interacts with both Msx1 and Pax9 to pattern the tooth developmental field. Developmental biology, 353 2, 344-53

Liu, Wenjin; Watson, Spencer S; Lan, Yu; Keene, Douglas R; Ovitt, Catherine E; Liu, Han; Schweitzer, Ronen; Jiang, Rulang 2010. The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. Molecular and cellular biology, 30 20, 4797-807

Chen, Jianquan; Lan, Yu; Baek, Jin-A; Gao, Yang; Jiang, Rulang 2009. Wnt/beta-catenin signaling plays an essential role in activation of odontogenic mesenchyme during early tooth development. Developmental biology, 334 1, 174-85

Gao, Yang; Lan, Yu; Ovitt, Catherine E; Jiang, Rulang 2009. Functional equivalence of the zinc finger transcription factors Osr1 and Osr2 in mouse development. Developmental biology, 328 2, 200-9

Lan, Yu; Jiang, Rulang 2009. Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowth. Development (Cambridge, England), 136 8, 1387-96

Richardson, Rebecca J; Dixon, Jill; Jiang, Rulang; Dixon, Michael J 2009. Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence. Human molecular genetics, 18 14, 2632-42

Xiong, Wei; He, Fenglei; Morikawa, Yuka; Yu, Xueyan; Zhang, Zunyi; Lan, Yu; Jiang, Rulang; Cserjesi, Peter; Chen, Yiping 2009. Hand2 is required in the epithelium for palatogenesis in mice. Developmental biology, 330 1, 131-41

Zhang, Zunyi; Lan, Yu; Chai, Yang; Jiang, Rulang 2009. Antagonistic actions of Msx1 and Osr2 pattern mammalian teeth into a single row. Science (New York, N.Y.), 323 5918, 1232-4

Liu, Wenjin; Lan, Yu; Pauws, Erwin; Meester-Smoor, Magda A; Stanier, Philip; Zwarthoff, Ellen C; Jiang, Rulang 2008. The Mn1 transcription factor acts upstream of Tbx22 and preferentially regulates posterior palate growth in mice. Development (Cambridge, England), 135 23, 3959-68

Chen, Jianquan; Bush, Jeffrey O; Ovitt, Catherine E; Lan, Yu; Jiang, Rulang 2007. The TGF-beta pseudoreceptor gene Bambi is dispensable for mouse embryonic development and postnatal survival. Genesis (New York, N.Y. : 2000), 45 8, 482-6

Lan, Yu; Wang, Qingru; Ovitt, Catherine E; Jiang, Rulang 2007. A unique mouse strain expressing Cre recombinase for tissue-specific analysis of gene function in palate and kidney development. Genesis (New York, N.Y. : 2000), 45 10, 618-24

Casey, Liam M; Lan, Yu; Cho, Eui-Sic; Maltby, Kathleen M; Gridley, Thomas; Jiang, Rulang 2006. Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development. Developmental dynamics : an official publication of the American Association of Anatomists, 235 7, 1830-44

James, Richard G; Kamei, Caramai N; Wang, Qingru; Jiang, Rulang; Schultheiss, Thomas M 2006. Odd-skipped related 1 is required for development of the metanephric kidney and regulates formation and differentiation of kidney precursor cells. Development (Cambridge, England), 133 15, 2995-3004

Jiang, Rulang; Bush, Jeffrey O; Lidral, Andrew C 2006. Development of the upper lip: morphogenetic and molecular mechanisms. Developmental dynamics : an official publication of the American Association of Anatomists, 235 5, 1152-66

Knight, Alexandra S; Schutte, Brian C; Jiang, Rulang; Dixon, Michael J 2006. Developmental expression analysis of the mouse and chick orthologues of IRF6: the gene mutated in Van der Woude syndrome. Developmental dynamics : an official publication of the American Association of Anatomists, 235 5, 1441-7

Lan, Yu; Ryan, Rosemary C; Zhang, Zunyi; Bullard, Steven A; Bush, Jeffrey O; Maltby, Kathleen M; Lidral, Andrew C; Jiang, Rulang 2006. Expression of Wnt9b and activation of canonical Wnt signaling during midfacial morphogenesis in mice. Developmental dynamics : an official publication of the American Association of Anatomists, 235 5, 1448-54

Liu, Han; Liu, Wenjin; Maltby, Kathleen M; Lan, Yu; Jiang, Rulang 2006. Identification and developmental expression analysis of a novel homeobox gene closely linked to the mouse Twirler mutation. Gene expression patterns : GEP, 6 6, 632-6

Alappat, Sylvia R; Zhang, Zunyi; Suzuki, Kentaro; Zhang, Xiaoyun; Liu, Hongbing; Jiang, Rulang; Yamada, Gen; Chen, YiPing 2005. The cellular and molecular etiology of the cleft secondary palate in Fgf10 mutant mice. Developmental biology, 277 1, 102-13

Vieira, Alexandre R; Avila, Joseph R; Daack-Hirsch, Sandra; Dragan, Ecaterina; Félix, Têmis M; Rahimov, Fedik; Harrington, Jill; Schultz, Rebecca R; Watanabe, Yoriko; Johnson, Marla; Fang, Jennifer; O'Brien, Sarah E; Orioli, Iêda M; Castilla, Eduardo E; Fitzpatrick, David R; Jiang, Rulang; Marazita, Mary L; Murray, Jeffrey C 2005. Medical sequencing of candidate genes for nonsyndromic cleft lip and palate. PLoS genetics, 1 6, e64

Wang, Qingru; Lan, Yu; Cho, Eui-Sic; Maltby, Kathleen M; Jiang, Rulang 2005. Odd-skipped related 1 (Odd 1) is an essential regulator of heart and urogenital development. Developmental biology, 288 2, 582-94

Bush, Jeffrey O; Lan, Yu; Jiang, Rulang 2004. The cleft lip and palate defects in Dancer mutant mice result from gain of function of the Tbx10 gene. Proceedings of the National Academy of Sciences of the United States of America, 101 18, 7022-7

Hadland, Brandon K; Huppert, Stacey S; Kanungo, Jyotshnabala; Xue, Yingzi; Jiang, Rulang; Gridley, Thomas; Conlon, Ronald A; Cheng, Alec M; Kopan, Raphael; Longmore, Gregory D 2004. A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development. Blood, 104 10, 3097-105

Lan, Yu; Ovitt, Catherine E; Cho, Eui-Sic; Maltby, Kathleen M; Wang, Qingru; Jiang, Rulang 2004. Odd-skipped related 2 (Osr2) encodes a key intrinsic regulator of secondary palate growth and morphogenesis. Development (Cambridge, England), 131 13, 3207-16

Bush, Jeffrey O; Maltby, Kathleen M; Cho, Eui-Sic; Jiang, Rulang 2003. The T-box gene Tbx10 exhibits a uniquely restricted expression pattern during mouse embryogenesis. Gene expression patterns : GEP, 3 4, 533-8

Krebs, Luke T; Iwai, Naomi; Nonaka, Shigenori; Welsh, Ian C; Lan, Yu; Jiang, Rulang; Saijoh, Yukio; O'Brien, Timothy P; Hamada, Hiroshi; Gridley, Thomas 2003. Notch signaling regulates left-right asymmetry determination by inducing Nodal expression. Genes & development, 17 10, 1207-12

Bush, Jeffrey O; Lan, Yu; Maltby, Kathleen M; Jiang, Rulang 2002. Isolation and developmental expression analysis of Tbx22, the mouse homolog of the human X-linked cleft palate gene. Developmental dynamics : an official publication of the American Association of Anatomists, 225 3, 322-6

Jiang R.;Norton C.;Copeland N.;Gilbert D.;Jenkins N.;Gridley T. 11-26-1998. Genomic organization, expression and chromosomal localization of the mouse Slug (Slugh) gene Biochimica et Biophysica Acta - Gene Structure and Expression, 1443 1-2, 251-254

Carver E.;Jiang R.;Lan Y.;Oram K.;Gridley T. 11-22-2001. The mouse Snail gene encodes a key regulator of the epithelial-mesenchymal transition Molecular and Cellular Biology, 21 23, 8184-8188

Lan Y.;Jiang R.;Shawber C.;Weinmaster G.;Gridley T. 11-15-1997. The Jagged2 gene maps to chromosome 12 and is a candidate for the igl and l sm mutations Mammalian Genome, 8 11, 875-876

Fu X.;Xu J.;Chaturvedi P.;Liu H.;Jiang R.;Lan Y. 11-01-2017. Identification of Osr2 Transcriptional Target Genes in Palate Development Journal of Dental Research, 96 12, 1451-1458

Li C.;Lan Y.;Jiang R. 10-01-2017. Molecular and Cellular Mechanisms of Palate Development Journal of Dental Research, 96 11, 1184-1191

Li C.;Lan Y.;Krumlauf R.;Jiang R. 10-01-2017. Modulating Wnt Signaling Rescues Palate Morphogenesis in Pax9 Mutant Mice Journal of Dental Research, 96 11, 1273-1281

Bell S.;Lan Y.;Jiang R.;Gridley T. 09-15-1998. Exclusion of Jagged2 as a candidate for the legless gene Mammalian Genome, 9 9, 778-779

Kwon H.J.E.;Jia S.;Lan Y.;Liu H.;Jiang R. 09-01-2017. Activin and Bmp4 Signaling Converge on Wnt Activation during Odontogenesis Journal of Dental Research, 96 10, 1145-1152

Jiang R.;Copeland N.;Gilbert D.;Jenkins N.;Gridley T. 09-01-1997. Genomic organization and chromosomal localization of the mouse snail (Sna) gene Mammalian Genome, 8 9, 686-688

Bae C.H.;Lee J.Y.;Kim T.H.;Baek J.A.;Lee J.C.;Yang X.;Taketo M.M.;Jiang R.;Cho E.S. 08-01-2013. Excessive Wnt/?-catenin signaling disturbs tooth-root formation Journal of Periodontal Research, 48 4, 405-410

Han L.;Xu J.;Grigg E.;Slack M.;Chaturvedi P.;Jiang R.;Zorn A. 07-01-2017. Osr1 functions downstream of Hedgehog pathway to regulate foregut development Developmental Biology, 427 1, 72-83

Jiang R.;Lan Y.;Norton C.;Sundberg J.;Gridley T. 06-15-1998. The slug gene is not essential for mesoderm or neural crest development in mice Developmental Biology, 198 2, 277-285

Liu Z.;Li C.;Xu J.;Lan Y.;Liu H.;Li X.;Maire P.;Wang X.;Jiang R. 05-01-2019. Crucial and Overlapping Roles of Six1 and Six2 in Craniofacial Development Journal of Dental Research, 98 5, 572-579

Jiang R.;Gridley T. 05-01-1997. Gene targeting: Things go better with Cre Current Biology, 7 5,

McCright B.;Gao X.;Shen L.;Lozier J.;Lan Y.;Maguire M.;Herzlinger D.;Weinmaster G.;Jiang R.;Gridley T. 04-02-2001. Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Development, 128 4, 491-502

Jiang R.;Lan Y.;Chapman H.;Shawber C.;Norton C.;Serreze D.;Weinmaster G.;Gridley T. 04-01-1998. Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice Genes and Development, 12 7, 1046-1057

Liu H.;Xu J.;Jiang R. 03-01-2019. Mkx-Deficient Mice Exhibit Hedgehog Signaling–Dependent Ectopic Ossification in the Achilles Tendons Journal of Bone and Mineral Research, 34 3, 557-569

Kim T.H.;Bae C.H.;Lee J.C.;Ko S.O.;Yang X.;Jiang R.;Cho E.S. 03-01-2013. ?-Catenin is required in odontoblasts for tooth root formation Journal of Dental Research, 92 3, 215-221

Lanford P.;Lan Y.;Jiang R.;Lindsell C.;Weinmaster G.;Gridley T.;Kelley M. 03-01-1999. Notch signalling pathway mediates hair cell development in mammalian cochlea Nature Genetics, 21 3, 289-292

Baek J.A.;Lan Y.;Liu H.;Maltby K.M.;Mishina Y.;Jiang R. 02-15-2011. Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation Developmental Biology, 350 2, 520-531

Xu J.;Liu H.;Lan Y.;Adam M.;Clouthier D.E.;Potter S.;Jiang R. 01-14-2019. Hedgehog signaling patterns the oral-aboral axis of the mandibular arch eLife, 8 ,

Kwon H.;Park E.;Jia S.;Liu H.;Lan Y.;Jiang R. 01-01-2015. Deletion of Osr2 partially rescues tooth development in Runx2 mutant mice Journal of Dental Research, 94 8, 1113-1119

Gao Y.;Lan Y.;Liu H.;Jiang R. 01-01-2011. The zinc finger transcription factors Osr1 and Osr2 control synovial joint formation Developmental Biology, 352 1, 83-91

Zhou J.;Gao Y.;Zhang Z.;Zhang Y.;Maltby K.;Liu Z.;Lan Y.;Jiang R. 01-01-2011. Osr2 acts downstream of Pax9 and interacts with both Msx1 and Pax9 to pattern the tooth developmenta Developmental Biology, 353 2, 344-353

Alappat S.;Zhang Z.;Suzuki K.;Zhang X.;Liu H.;Jiang R.;Yamada G.;Chen Y. 01-01-2005. The cellular and molecular etiology of the cleft secondary palate in Fgf10 mutant mice Developmental Biology, 277 1, 102-113

Lan Y.;Kingsley P.;Cho E.;Jiang R. 01-01-2001. Osr2, a new mouse gene related to Drosophila odd-skipped, exhibits dynamic expression patterns durin Mechanisms of Development, 107 1-2, 175-179

Lan, Yu; Jia, Shihai; Jiang, Rulang . Molecular patterning of the mammalian dentition. Seminars in cell & developmental biology, 25-26 , 61-70