Fan Laboratory

Most Recent Publications

2024

Wang, Xiaohong; Du, Wa; Li, Yutian; Yang, Hui-Hui; Zhang, Yu; Akbar, Rubab; Morgan, Hannah; Peng, Tianqing; Chen, Jing; Sadayappan, Sakthivel; Hu, Yueh-Chiang; Fan, Yanbo; Huang, Wei; Fan, Guo-Chang 2024. Macrophage-enriched Sectm1a promotes efficient efferocytosis to attenuate ischemia/reperfusion-induced cardiac injury. JCI insight, 9 5,

Wang, Chenran; Nagayach, Aarti; Patel, Harsh; Dao, Lan; Zhu, Hui; Wasylishen, Amanda R; Fan, Yanbo; Kendler, Ady; Guo, Ziyuan 2024. Utilizing human cerebral organoids to model breast cancer brain metastasis in culture. Breast cancer research : BCR, 26 1, 108

2023

Ren, Lu; Du, Wa; Song, Dan; Lu, Haocheng; Hamblin, Milton H; Wang, Chenran; Du, Chunying; Fan, Guo-Chang; Becker, Richard C; Fan, Yanbo 2023. Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice. iScience, 26 1, 105769

Feng, Yuliang; Cai, Liuyang; Pook, Martin; Liu, Feng; Chang, Chao-Hui; Mouti, Mai Abdel; Nibhani, Reshma; Militi, Stefania; Dunford, James; Philpott, Martin; Fan, Yanbo; Fan, Guo-Chang; Liu, Qi; Qi, Jun; Wang, Cheng; Hong, Wanzi; Morgan, Hannah; Wang, Mingyang; Sadayappan, Sakthivel; Jegga, Anil G; Oppermann, Udo; Wang, Yigang; Huang, Wei; Jiang, Lei; Pauklin, Siim 2023. BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma. Gastroenterology, ,

Zhao, Hongyan; Wang, Peng; Wang, Xiaohong; Du, Wa; Yang, Hui-Hui; Liu, Yueying; Cui, Shu-Nan; Huang, Wei; Peng, Tianqing; Chen, Jing; Gao, Chen; Wang, Yigang; Sadayappan, Sakthivel; Ma, Chengen; Fan, Yanbo; Wang, Chunting; Fan, Guo-Chang 2023. Lipocalin 10 is essential for protection against inflammation-triggered vascular leakage by activating LDL receptor-related protein 2-slingshot homologue 1 signalling pathway. Cardiovascular research, 119 10, 1981-1996

Feng, Yuliang; Cai, Liuyang; Pook, Martin; Liu, Feng; Chang, Chao-Hui; Mouti, Mai Abdel; Nibhani, Reshma; Wu, Shihong; Deng, Siwei; Militi, Stefania; Dunford, James; Philpott, Martin; Fan, Yanbo; Fan, Guo-Chang; Liu, Qi; Qi, Jun; Sadayappan, Sakthivel; Jegga, Anil G; Oppermann, Udo; Wang, Yigang; Huang, Wei; Jiang, Lei; Pauklin, Siim 2023. BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma. bioRxiv : the preprint server for biology, ,

Tang, Xin; Walter, Ellen; Wohleb, Eric; Fan, Yanbo; Wang, Chenran 2023. ATG5 (autophagy related 5) in microglia controls hippocampal neurogenesis in Alzheimer disease. Autophagy, , 1-16

2022

Li, Qianqian; Li, Yutian; Huang, Wei; Wang, Xiaohong; Liu, Zhenling; Chen, Jing; Fan, Yanbo; Peng, Tianqing; Sadayappan, Sakthivel; Wang, Yigang; Fan, Guo-Chang 2022. Loss of Lipocalin 10 Exacerbates Diabetes-Induced Cardiomyopathy via Disruption of Nr4a1-Mediated Anti-Inflammatory Response in Macrophages. Frontiers in immunology, 13 , 930397

2021

Liu, Yuhao; Zhao, Ying; Shukha, Yousef; Lu, Haocheng; Wang, Lu; Liu, Zhipeng; Liu, Cai; Zhao, Yang; Wang, Huilun; Zhao, Guizhen; Liang, Wenying; Fan, Yanbo; Chang, Lin; Yurdagul, Arif; Pattillo, Christopher B; Orr, A Wayne; Aviram, Michael; Wen, Bo; Garcia-Barrio, Minerva T; Zhang, Jifeng; Liu, Wanqing; Sun, Duxin; Hayek, Tony; Chen, Y Eugene; Rom, Oren 2021. Dysregulated oxalate metabolism is a driver and therapeutic target in atherosclerosis. Cell reports, 36 4, 109420

Zhao, Guizhen; Chang, Ziyi; Zhao, Yang; Guo, Yanhong; Lu, Haocheng; Liang, Wenying; Rom, Oren; Wang, Huilun; Sun, Jinjian; Zhu, Tianqing; Fan, Yanbo; Chang, Lin; Yang, Bo; Garcia-Barrio, Minerva T; Chen, Y Eugene; Zhang, Jifeng 2021. KLF11 protects against abdominal aortic aneurysm through inhibition of endothelial cell dysfunction. JCI insight, 6 5,

Lu, Haocheng; Sun, Jinjian; Hamblin, Milton H; Chen, Y Eugene; Fan, Yanbo 2021. Transcription factor EB regulates cardiovascular homeostasis. EBioMedicine, 63 , 103207

Liang, Wenying; Lu, Haocheng; Sun, Jinjian; Zhao, Guizhen; Wang, Huilun; Guo, Yanhong; Eitzman, Daniel; Chen, Y Eugene; Fan, Yanbo#; Zhang, Jifeng 2021. KLF11 Protects against Venous Thrombosis via Suppressing Tissue Factor Expression. Thrombosis and haemostasis, ,

Du, Wa; Ren, Lu; Hamblin, Milton H; Fan, Yanbo 2021. Endothelial Cell Glucose Metabolism and Angiogenesis. Biomedicines, 9 2,

Lu, Haocheng; Du, Wa; Ren, Lu; Hamblin, Milton H; Becker, Richard C; Chen, Y Eugene; Fan, Yanbo 2021. Vascular Smooth Muscle Cells in Aortic Aneurysm: From Genetics to Mechanisms. Journal of the American Heart Association, , e023601

Fan, Yanbo; Wolford, Brooke N; Lu, Haocheng; Liang, Wenying; Sun, Jinjian; Zhou, Wei; Rom, Oren; Mahajan, Anubha; Surakka, Ida; Graham, Sarah E; Liu, Zhipeng; Kim, Hyunbae; Ramdas, Shweta; Fritsche, Lars G; Nielsen, Jonas B; Gabrielsen, Maiken Elvestad; Hveem, Kristian; Yang, Dongshan; Song, Jun; Garcia-Barrio, Minerva T; Zhang, Jifeng; Liu, Wanqing; Zhang, Kezhong; Willer, Cristen J; Chen, Y Eugene 2021. Type 2 diabetes sex-specific effects associated with E167K coding variant in TM6SF2. iScience, 24 11, 103196

Liang, Wenying; Lu, Haocheng; Sun, Jinjian; Zhao, Guizhen; Wang, Huilun; Guo, Yanhong; Eitzman, Daniel; Chen, Y Eugene; Fan, Yanbo; Zhang, Jifeng 2021. KLF11 Protects against Venous Thrombosis via Suppressing Tissue Factor Expression. Thrombosis and haemostasis, ,