Publications

Representative publications are listed below
Complete list of our publications, please visit: Perez-Tilve Publications (Pubmed)

Morano R, Yates E, Barnes R, Wohleb ES, Perez-Tilve D. Influence of nutritional status and leptin action on Agrp and Pomc co-expression in hypothalamic melanocortin system neurons. Neuroendocrinology. 2021 Apr 27. doi: 10.1159/000516834. Epub ahead of print. PMID: 33906196.

Zhang Q, Delessa CT, Augustin R, Bakhti M, Colldén G, Drucker DJ, Feuchtinger A, Caceres CG, Grandl G, Harger A, Herzig S, Hofmann S, Holleman CL, Jastroch M, Keipert S, Kleinert M, Knerr PJ, Kulaj K, Legutko B, Lickert H, Liu X, Luippold G, Lutter D, Malogajski E, Medina MT, Mowery SA, Blutke A, Perez-Tilve D, Salinno C, Sehrer L, DiMarchi RD, Tschöp MH, Stemmer K, Finan B, Wolfrum C, Müller TD. The glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake via CNS-GIPR signaling. Cell Metab. 2021 Apr 6;33(4):833-844.e5. doi: 10.1016/j.cmet.2021.01.015. Epub 2021 Feb 10. PMID: 33571454; PMCID: PMC8035082.

Zizzari P, He R, Falk S, Bellocchio L, Allard C, Clark S, Lesté-Lasserre T, Marsicano G, Clemmensen C, Perez-Tilve D, Finan B, Cota D, Quarta C. CB1 and GLP-1 Receptors Cross Talk Provides New Therapies for Obesity. Diabetes. 2021 Feb;70(2):415-422. doi: 10.2337/db20-0162. Epub 2020 Nov 3. PMID: 33144338.

Sorrell J, Yates E, Rivir M, Woods SC, Hogenesch JB, Perez-Tilve D. The central melanocortin system mediates the benefits of time-restricted feeding on energy balance. Physiol Behav. 2020 Dec 1;227:113132. doi: 10.1016/j.physbeh.2020.113132. Epub 2020 Aug 10. PMID: 32791179.

Holland J, Sorrell J, Yates E, Smith K, Arbabi S, Arnold M, Rivir M, Morano R, Chen J, Zhang X, Dimarchi R, Woods SC, Sanchez-Gurmaches J, Wohleb E, Perez-Tilve D. A Brain-Melanocortin-Vagus Axis Mediates Adipose Tissue Expansion Independently of Energy Intake. Cell Rep. 2019 May 21;27(8):2399-2410.e6. doi: 10.1016/j.celrep.2019.04.089. PMID: 31116984; PMCID: PMC6550338.

Mroz PA, Finan B, Gelfanov V, Yang B, Tschöp MH, DiMarchi RD, Perez-Tilve D. Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism. Mol Metab. 2019 Feb;20:51-62. doi: 10.1016/j.molmet.2018.12.001. Epub 2018 Dec 5. PMID: 30578168; PMCID: PMC6358549.

Rivero-Gutierrez B, Haller A, Holland J, Yates E, Khrisna R, Habegger K, Dimarchi R, D'Alessio D, Perez-Tilve D. Deletion of the glucagon receptor gene before and after experimental diabetes reveals differential protection from hyperglycemia. Mol Metab. 2018 Nov;17:28-38. doi: 10.1016/j.molmet.2018.07.012. Epub 2018 Aug 20. PMID: 30170980; PMCID: PMC6197675.

Kim T, Holleman CL, Nason S, Arble DM, Ottaway N, Chabenne J, Loyd C, Kim JA, Sandoval D, Drucker DJ, DiMarchi R, Perez-Tilve D, Habegger KM. Hepatic Glucagon Receptor Signaling Enhances Insulin-Stimulated Glucose Disposal in Rodents. Diabetes. 2018 Nov;67(11):2157-2166. doi: 10.2337/db18-0068. Epub 2018 Aug 27. PMID: 30150304; PMCID: PMC6198333.

Kim T, Nason S, Holleman C, Pepin M, Wilson L, Berryhill TF, Wende AR, Steele C, Young ME, Barnes S, Drucker DJ, Finan B, DiMarchi R, Perez-Tilve D, Tschöp M, Habegger KM. Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21. Diabetes. 2018 Sep;67(9):1773-1782. doi: 10.2337/db17-1502. Epub 2018 Jun 20. PMID: 29925501; PMCID: PMC6110317.

Peng J, Li Y, Wang X, Deng S, Holland J, Yates E, Chen J, Gu H, Essandoh K, Mu X, Wang B, McNamara RK, Peng T, Jegga AG, Liu T, Nakamura T, Huang K, Perez-Tilve D, Fan GC. An Hsp20-FBXO4 Axis Regulates Adipocyte Function through Modulating PPARγ Ubiquitination. Cell Rep. 2018 Jun 19;23(12):3607-3620. doi: 10.1016/j.celrep.2018.05.065. PMID: 29925002; PMCID: PMC6091893.

Mahbod P, Smith EP, Fitzgerald ME, Morano RL, Packard BA, Ghosal S, Scheimann JR, Perez-Tilve D, Herman JP, Tong J. Desacyl Ghrelin Decreases Anxiety-like Behavior in Male Mice. Endocrinology. 2018 Jan 1;159(1):388-399. doi: 10.1210/en.2017-00540. PMID: 29155981; PMCID: PMC5761608.